Biochemistry of the Mevalonic Acid Pathway to Terpenoids:
Biochemistry of the Mevalonic Acid Pathway to Terpenoids:Auflage 1990
Modulation of Breast Cancer Genes by Conjugated Linoleic Acid:Modulation of Genes Involved in the Apoptotic Pathway in Human Breast Cancer by Conjugated Linoleic Acid and Fatty Acids Barun Majumder
New therapeutic compounds against tuberculosis:In silico design of new therapeutic compounds targeting biosynthetic pathway of Mycolic acid in M. tuberculosis Asra´a Adnan Abdul-Jalil, Zahra Mahmoud Al-Khafaji
This volume explores techniques used to detect lipids attached to proteins, to analyze the function of lipid modifications, and to characterize the enzymes that add and remove lipids from proteins. The book is organized into seven parts: Part One describes chemically-based strategies to identify substrates for protein lipidation that can be applied to individual proteins or globally using proteomics. Part Two focuses on the enzymes that remove fatty acids from proteins and provides methods to monitor protein biogenesis and palmitate turnover. Part Three addresses biochemical and cellular characterization of DHHC S-acyltransferases, a family of enzymes with 23 members encoded by the human genome. Part Four presents the SwissPalm 2 database and tips on how to use it effectively. Part Five focuses on fatty acylation that occurs in the lumen of the secretory pathway. Parts Six and Seven conclude the book with methods to produce and assay lipid-modified and integral membrane proteins. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Protein Lipidation: Methods and Protocols is a valuable resource for experts in the field and for investigators who encounter protein lipidation through their research on a particular cellular process or favorite protein.
Dr. Izabella Wentz, the author of the phenomenal New York Times best seller Hashimoto´s Thyroiditis, returns with a long-awaited, groundbreaking prescription to reverse the symptoms of this serious autoimmune condition that is becoming one of the country´s fastest growing diseases. More than 35 million Americans currently suffer from Hashimoto´s - an autoimmune disease that affects the thyroid gland and causes the body to attack its own cells. To alleviate the symptoms of this debilitating condition - including chronic cough, acid reflux, IBS, allergies, chronic pain, hair loss, brain fog, and forgetfulness - patients are often prescribed synthetic hormones that have numerous life-altering side effects. But there is a better way. Diagnosed with Hashimoto´s at 27, pharmacist Dr. Izabella Wentz knows firsthand the effects of the disease as well as the value - and limitations - of medication. The key to improved health, she argues, involves lifestyle interventions. In Hashimoto´s Protocol, she outlines a proven treatment that has helped thousands heal and many others feel better - in as fast as 90 days. Drawing on her own personal experience as well as her work consulting with thousands of patients, Hashimoto´s Protocol offers a practical pathway for healing and reversing the autoimmune damage at the root of the disease. The first step is a quick-start two-week detox that includes foods to eat and inflammatory foods to avoid, advice on supplements to support the liver, and an adrenal recovery plan. Next, listeners create a personalized plan with foods, supplements, and other lifestyle interventions tailored to their bodies´ own unique Hashimoto´s triggers, which they can identify using self-tests included in the book. Hashimoto´s Protocol also features original recipes. Grounded in the latest science, Hashimoto´s Protocol is the first book to offer a proven protocol by an acknowledged 1. Language: English. Narrator: Erin Bennett. Audio sample: http://samples.audible.de/bk/harp/005858/bk_harp_005858_sample.mp3. Digital audiobook in aax.